Refractive error, ocular biometry, and lens opalescence in an adult population: The Los Angeles Latino Eye Study
Refractive error, ocular biometry, and lens opalescence in an adult population: The Los Angeles Latino Eye Study
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DOI：
10.1167/iovs.05-0435
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发表时间：
2005-12-01
影响因子：
4.4
通讯作者：
Varma, R
中科院分区：
文献类型：
--
作者：
Shufelt, C;Fraser-Bell, S;Varma, R
目的.描述拉丁美洲成年人人群样本中屈光不正、眼生物测量和透镜浑浊度（NOP）的年龄和性别相关差异。还评估了与年龄相关的屈光差异的决定因素。洛杉矶拉丁裔眼科研究（LALES）是一项针对40岁及以上拉丁裔人群的研究，参与者接受眼科检查，包括超声测量眼轴长度（AL）、玻璃体腔深度（VCD）、前房深度（ACD）、透镜厚度（LT）以及非睫状肌麻痹自动验光和主观验光。使用自动验光仪测量角膜曲率/屈光度（CP）。由眼科医生使用透镜混浊分类系统II在裂隙灯下对NOP进行分级。计算了年龄和性别相关的差异。多元回归模型用于确定年龄相关屈光差异的决定因素。在6357名LALES参与者中，5588名具有生物特征数据的有晶状体眼个体被纳入本分析。与年轻个体相比，老年个体具有较浅的ACD、较厚的晶状体、较多的NOP和较多的远视（P < 0.001）。AL无年龄差异（P >= 0.05）.女性AL明显短于男性，ACD和VCD明显浅于男性（P
PURPOSE. To characterize age- and gender-related differences in refractive error, ocular biometry, and lens opalescence (NOP) in a population-based sample of adult Latinos. Also assessed were the determinants of age- related refractive differences.METHODS. Participants in the Los Angeles Latino Eye Study (LALES), a population-based study of Latinos aged 40 years and more, underwent an ophthalmic examination, including ultrasonic measurements of axial length (AL), vitreous chamber depth (VCD), anterior chamber depth (ACD), lens thickness (LT), and noncycloplegic automated and subjective refraction. Corneal curvature/power (CP) was measured using an autorefractor. NOP was graded at the slit lamp by an ophthalmologist using the Lens Opacity Classification System II. Age- and gender-related differences were calculated. Multiple regression models were used to identify the determinants of age-related refractive differences.RESULTS. Of the 6357 LALES participants, 5588 phakic individuals with biometric data were included in this analysis. Older individuals had shallower ACDs, thicker lenses, more NOP, and more hyperopia compared to younger individuals (P < 0.001). There was no age- related difference in AL (P >= 0.05). Women had significantly shorter AL, shallower ACD and VCD, than did men (P