Calculations and measurements of the scintillator-to-water stopping power ratio of liquid scintillators for use in proton radiotherapy.
Calculations and measurements of the scintillator-to-water stopping power ratio of liquid scintillators for use in proton radiotherapy.
复制标题
用于质子放射治疗的液体闪烁体的闪烁体与水的阻止本领比的计算和测量。
DOI：
10.1016/j.nima.2014.12.004
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发表时间：
2015
期刊：
影响因子：
--
通讯作者：
Beddar,Sam
中科院分区：
文献类型：
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作者：
Ingram,WScott;Robertson,Daniel;Beddar,Sam
液体闪烁器是一种很有前途的高分辨率三维质子治疗剂量学探测器。由于闪烁体包括探测器的有效体积和体模材料，因此理想的闪烁体将在其放射性特性方面表现出水等效性。其中最基本的是闪烁体的阻止本领。本研究的目的是比较计算和测量的质子-水阻功率比，以评估液体质子计数器BC-531和OptiPhase HiSafe 3的质子剂量测定的适用性。我们还测量了两个闪烁器的相对闪烁输出。计算和测量均表明，OptiPhase的线性阻止本领比BC-531更接近水。BC-531具有稍高的闪烁输出。OptiPhase可以与高浓度的水混合，这进一步提高了其对水的阻隔能力比。然而，这会导致溶液变得浑浊，这对探测器的闪烁输出和空间分辨率有负面影响。OptiPhase比BC-531更适合用于质子剂量测定，因为其密度和电离器与水的阻挡能力比更接近水当量。
Liquid scintillators are a promising detector for high-resolution three-dimensional proton therapy dosimetry. Because the scintillator comprises both the active volume of the detector and the phantom material, an ideal scintillator will exhibit water equivalence in its radiological properties. One of the most fundamental of these is the scintillator’s stopping power. The objective of this study was to compare calculations and measurements of scintillator-to-water stopping power ratios to evaluate the suitability of the liquid scintillators BC-531 and OptiPhase HiSafe 3 for proton dosimetry. We also measured the relative scintillation output of the two scintillators. Both calculations and measurements show that the linear stopping power of OptiPhase is significantly closer to water than that of BC-531. BC-531 has a somewhat higher scintillation output. OptiPhase can be mixed with water at high concentrations, which further improves its scintillator-to-water stopping power ratio. However, this causes the solution to become cloudy, which has a negative impact on the scintillation output and spatial resolution of the detector. OptiPhase is preferred over BC-531 for proton dosimetry because its density and scintillator-to-water stopping power ratio are more water equivalent.