Prevalence and predictors of post-traumatic stress symptoms in adolescent and young adult cancer survivors: a 1-year follow-up study
Prevalence and predictors of post-traumatic stress symptoms in adolescent and young adult cancer survivors: a 1-year follow-up study
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DOI：
10.1002/pon.3217
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发表时间：
2013-08-01
期刊：
影响因子：
3.6
通讯作者：
Cole, Steven
中科院分区：
文献类型：
--
作者：
Kwak, Minyoung;Zebrack, Brad J.;Cole, Steven
目的创伤后应激症状（PTSS）已被确定为癌症幸存者痛苦的一个有意义的指标。与儿童癌症的年轻成年幸存者不同，青少年和年轻人（AYA）被诊断患有癌症的年轻人面临着独特的心理社会问题;然而，很少有关于AYA人群PTSS的已发表研究。本研究探讨PTSS的患病率和预测因素之间AYAs与cancer.Methods的纵向研究的一部分，AYAs与癌症，151例患者年龄在15- 39岁完成邮寄调查，在6个月和12个月后诊断。在诊断后6个月和12个月评估PTSS的严重程度。多元回归分析进行调查的社会人口学和临床特征的预测效果PTSS随时间的变化，在6个月和12个月，分别为39%和44%的参与者报告中度至重度水平的PTSS; 29%的PTSS水平提示创伤后应激障碍。6个月和12个月之间PTSS的严重程度无显著差异。回归分析表明，更多的副作用与6个月时较高的PTSS水平相关。目前正在接受治疗、接受手术治疗、确诊为生存率为90-100%的癌症类型、未就业/未上学、6个月时PTSS较高与12个月时PTSS较高相关。建议制定早期干预措施，以减少AYA患者在治疗中的痛苦。版权所有（c）2012约翰威利父子有限公司
Objectives Post-traumatic stress symptoms (PTSS) have been identified as a meaningful indicator of distress in cancer survivors. Distinct from young adult survivors of childhood cancer, young people diagnosed with cancer as adolescents and young adults (AYAs) face unique psychosocial issues; however, there is little published research of PTSS in the AYA population. This study examines prevalence and predictors of PTSS among AYAs with cancer.Methods As part of a longitudinal study of AYAs with cancer, 151 patients aged 15-39years completed mailed surveys at 6 and 12months post-diagnosis. Severity of PTSS was estimated at 6 and 12months post-diagnosis. Multiple regression analyses were conducted to investigate the predictive effects of socio-demographic and clinical characteristics on changes in PTSS over time.Results At 6 and 12months, respectively, 39% and 44% of participants reported moderate to severe levels of PTSS; 29% had PTSS levels suggestive of post-traumatic stress disorder. No significant differences in severity of PTSS between 6 and 12months were observed. Regression analyses suggested that a greater number of side effects were associated with higher levels of PTSS at 6months. Currently receiving treatment, having surgical treatment, diagnosis of a cancer type with a 90-100% survival rate, remaining unemployed/not in school, and greater PTSS at 6months were associated with higher levels of PTSS at 12months.Conclusions Post-traumatic stress symptoms were observed as early as 6months following diagnosis and remained stable at 12-month follow-up. The development of early interventions for reducing distress among AYA patients in treatment is recommended. Copyright (c) 2012 John Wiley & Sons, Ltd.