COCHLEAR DAMAGE FOLLOWING INTERRUPTED EXPOSURE TO HIGH-FREQUENCY NOISE
COCHLEAR DAMAGE FOLLOWING INTERRUPTED EXPOSURE TO HIGH-FREQUENCY NOISE
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DOI：
10.1016/0378-5955(87)90172-9
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发表时间：
1987-01-01
期刊：
影响因子：
2.8
通讯作者：
GRUNER, MM
中科院分区：
文献类型：
--
作者：
BOHNE, BA;YOHMAN, L;GRUNER, MM
四组龙猫被置于中心频率为4 kHz、声压级为80或86 dB SPL的噪声频带中，在连续6小时的暴露间隔中分别休息18、42或162小时。这些耳朵的损伤与连续接触总能量相等的耳朵的损伤进行了比较。在连续和间断暴露的耳朵中也发现了相同的细胞损失模式。然而，在所有接受中断暴露的耳朵中，基底部病变的发生率和平均大小都减少了。研究发现，在连续6小时的高频噪声暴露之间，18小时的休息可以显著保护栗鼠耳蜗基底部免受损伤。
Four groups of chinchillas were exposed to an octave band of noise with a center frequencey of 4 kHz and a sound pressure level of 80 or 86 dB SPL on interrupted schedules with 18, 42 or 162 h of rest between successive 6-h exposures. Damage in these ears was compared to that in ears receiving continuous exposures which were equal in total energy. The same pattern of cell loss was found in ears damaged by continuous and interrupted exposures. However, both the incidence and average size of the lesion in the basal turn were reduced in all ears receiving interrupted exposures. Eighteen hours of rest between successive 6-h, high-frequency noise exposures was found to provide significant protection from damage for the basal turn of the chinchilla cochlea.