DRUGS, INCLUDING ALCOHOL, THAT ACT AS RISK-FACTORS FOR CATARACT, AND POSSIBLE PROTECTION AGAINST CATARACT BY ASPIRIN-LIKE ANALGESICS AND CYCLOPENTHIAZIDE
DRUGS, INCLUDING ALCOHOL, THAT ACT AS RISK-FACTORS FOR CATARACT, AND POSSIBLE PROTECTION AGAINST CATARACT BY ASPIRIN-LIKE ANALGESICS AND CYCLOPENTHIAZIDE
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DOI：
10.1136/bjo.72.11.809
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发表时间：
1988-11-01
影响因子：
4.1
通讯作者：
VANHEYNINGEN, R
中科院分区：
文献类型：
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作者：
HARDING, JJ;VANHEYNINGEN, R
英国牛津郡的一项白内障病例对照研究探讨了与各种药物相关的风险和益处。利尿剂螺内酯、硝苯地平等类固醇、大量吸烟和喝啤酒与风险增加有关。另一方面，阿司匹林类镇痛药（扑热息痛、布洛芬、阿司匹林等）似乎可以预防白内障。环哌噻嗪似乎提供了类似的保护。
A case-control study of cataract in Oxfordshire [England, UK] explored the risks and benefits associated with a variety of drugs. Steroids including the diuretic spironolactone, nifedipine, heavy smoking, and beer drinking were associated with a raised risk. On the other hand aspirin-like analgesics (paracetamol, ibuprofen, aspirin, etc.) appeared to protect against cataract. Cyclopenthiazide appeared to provide a similar protection.