Anal Douche Practices and Willingness to Use a Rectal Microbicide Enema for HIV Prevention and Associated Factors Among an Internet Sample of HIV-Negative and HIV-Discordant Male Couples in the US.
Anal Douche Practices and Willingness to Use a Rectal Microbicide Enema for HIV Prevention and Associated Factors Among an Internet Sample of HIV-Negative and HIV-Discordant Male Couples in the US.
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DOI：
10.1007/s10461-015-1250-4
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发表时间：
2016-11
影响因子：
4.4
通讯作者：
Petroll AE
中科院分区：
文献类型：
--
作者：
Mitchell JW;Sophus AI;Lee JY;Petroll AE
相当大比例的男男性接触者从他们的主要关系伙伴那里感染了艾滋病毒。目前正在研究直肠杀微生物剂，以确定其预防艾滋病毒的效果，但男性夫妇使用直肠杀菌剂的意愿在很大程度上尚不清楚。来自代表631名HIV阴性男性的333对HIV阴性和HIV不和谐男性夫妇的二元数据被用来评估肛门冲洗做法和使用直肠杀菌剂预防HIV的意愿。17%的男性在与主要伴侣发生肛交前100%会冲洗。在那些在他们的关系之外发生性行为的人中，36%的人在与临时的MSM伴侣发生肛交之前100%地冲洗过。大多数男性(63%)表示愿意在肛交前使用理论上有效的直肠杀菌剂来预防艾滋病毒。如果发现有效，作为肛门冲洗的直肠杀菌剂可能是一些已经进行肛门冲洗的男男性接触者可以接受的预防艾滋病毒的方式。了解目前的冲洗做法对于成功促进直肠杀菌剂的吸收将是重要的。
A significant proportion of MSM acquire HIV from their primary relationship partners. Rectal microbicides are currently being studied to determine their efficacy for HIV prevention, yet willingness to use rectal microbicides among male couples is largely unknown. Dyadic data from 333 HIV-negative and HIV-discordant male couples, representing 631 HIV-negative men, were used to assess anal douching practices and willingness to use a rectal microbicide for HIV prevention. 17% of men douched 100% of the time before having anal sex within their primary partner. Among those who had sex outside of their relationship, 36% had douched 100% of the time before having anal sex with a casual MSM partner. Most men (63%) indicated a willingness to use a theoretically effective rectal microbicide prior to anal sex for HIV prevention. If found effective, rectal microbicides delivered as an anal douche may be an acceptable format for HIV prevention to some MSM who already engage in anal douching. Understanding current douching practices will be important in successfully promoting the uptake of rectal microbicides.