Unexplained gonad alterations in whitefish (Coregonus spp.) from Lake Thun, Switzerland: Levels of persistent organic pollutants in different morphs
Unexplained gonad alterations in whitefish (Coregonus spp.) from Lake Thun, Switzerland: Levels of persistent organic pollutants in different morphs
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DOI：
10.1016/j.chemosphere.2008.09.058
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发表时间：
2009-01-01
期刊：
影响因子：
8.8
通讯作者：
Hungerbuehler, Konrad
中科院分区：
文献类型：
--
作者：
Bogdal, Christian;Naef, Michael;Hungerbuehler, Konrad
自2000年以来，一个令人惊讶的高数量的宏观性腺改变已报告在白鱼（白鲑属）。瑞士图恩湖这种独特的现象仍然无法解释，并引起了公众的广泛关注。作为这些影响的一个可能触发因素，已经讨论了作为内分泌干扰物存在于湖中的持久性、生物累积性和有毒化合物。在这项研究中，检查了图恩湖白鱼的两种形态中选定的持久性有机污染物的浓度，并调查了它们与观察到的异常的联系。分析的化合物类别包括多氯联苯、多氯二苯并对二恶英和二苯并呋喃、多氯萘、多溴二苯醚和六溴环十二烷。在所有样品中鉴定了目标物质，并且所分析的化合物的浓度彼此之间高度相关。这些相关性表明，分析的物质在整个湖泊中具有相同的分布模式，吸收，积累和消除过程是相似的。两种白鱼的分析形态之间存在显着差异的污染物水平的样本内，最有可能是由于不同的年龄，食物模式和生长速度。在污染物水平之间没有差异，观察到异常的性腺和鱼类与正常的性腺，这表明没有因果关系之间的联系，调查的亲脂性有机卤素化合物存在于鱼类和观察到的性腺异常白鱼图恩湖。与现有数据的比较表明，图恩湖白鲑体内的浓度处于瑞士湖泊或欧洲沃茨白鲑体内污染物水平的下限。(C)2008爱思唯尔有限公司保留所有权利。
Since 2000, a surprisingly high number of macroscopical gonad alterations has been reported in whitefish (Coregonus spp.) from Lake Thun, Switzerland. This unique phenomenon is still unexplained and has received much public attention. As one possible trigger for these effects, the presence of persistent, bioaccumulative and toxic compounds acting as endocrine disruptors in the lake has been discussed. In this study, concentrations of selected persistent organic pollutants were examined in two morphs of whitefish from Lake Thun and their link to the observed abnormalities was investigated. Analyzed compound classes included polychlorinated biphenyls, polychlorinated dibenzo-p-dioxins and dibenzofurans, polychlorinated naphthalenes, polybrominated diphenyl ethers and hexabromocyclododecanes. The target substances were identified in all samples and concentrations of the analyzed compounds were highly correlated among each other. These correlations show that the analyzed substances have the same distribution pattern throughout the lake and that uptake, accumulation and elimination processes are similar. Significant differences in contaminant levels within the samples existed between the two analyzed morphs of whitefish, most likely due to different age, food patterns and growth rate. No difference in contaminant levels was observed between fish with abnormal gonads and fish with normal gonads, suggesting no causal link between the investigated lipophilic organohalogen compounds present in fish and the observed gonad abnormalities in whitefish from Lake Thun. A comparison to existing data shows that concentrations in Lake Thun whitefish are at the lower bound of contaminant levels in whitefish from Swiss lakes or from European waters. (C) 2008 Elsevier Ltd. All rights reserved.