Ophthalmic findings in Apert syndrome prior to craniofacial surgery
Ophthalmic findings in Apert syndrome prior to craniofacial surgery
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DOI：
10.1016/j.ajo.2006.02.046
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发表时间：
2006-08-01
影响因子：
4.2
通讯作者：
David, David
中科院分区：
文献类型：
--
作者：
Khong, Jwu Jin;Anderson, Peter;David, David
目的：确定阿佩尔综合征患者在颅面手术前的眼科检查结果。设计：一项横断面回顾性研究。方法：对澳大利亚颅面科 63 例（27 名男性，36 名女性）未接受颅面手术的阿佩尔综合征病例进行回顾性分析。记录人口统计学数据、就诊年龄和首次就诊时的眼科检查结果。 结果：在平均年龄 4 岁和中位年龄 1 岁的患者中，至少 14% 的患者患有弱视，60% 的患者患有斜视，19% 的患者患有双眼对称。斜视，34%的眼睛患有屈光不正。至少 13% 的患者出现暴露性角膜病变和角膜疤痕，至少 8% 的患者出现视神经萎缩。 结论：这项研究表明，阿佩尔综合征患者由于屈光不正、斜视和屈光不正的患病率较高，存在弱视风险。斜视。暴露性角膜病变和角膜疤痕常见。
PURPOSE: To determine ophthalmic findings in patients with Apert syndrome before craniofacial surgery. DESIGN: A cross-sectional retrospective study.METHODS: Review of 63 cases (27 males, 36 females) with Apert syndrome without craniofacial surgery from the Australian Craniofacial Unit. Demographic data, age of presentation, and ophthalmic findings at the first presentation were recorded.RESULTS: At a mean age of four years and median age of one year, at least 14% of patients had amblyopia, 60% of patients had strabismus, 19% of patients had anisome. tropia, and 34% of eyes had ametropia. Exposure keratopathy and corneal scarring occurred in at least 13% of patients and optic atrophy in at least 8% of patients.CONCLUSIONS: This study demonstrated that patients with Apert syndrome were at risk of amblyopia because of high prevalence of refractive errors, strabismus, and anisome. tropia. Exposure keratopathy and corneal scarring occurred commonly.