Sedative, hypnotic, and antianxiety medication use in an aging cohort over ten years: A racial comparison
Sedative, hypnotic, and antianxiety medication use in an aging cohort over ten years: A racial comparison
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DOI：
10.1111/j.1532-5415.2000.tb04782.x
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发表时间：
2000-09-01
影响因子：
6.3
通讯作者：
Hanlon, JT
中科院分区：
文献类型：
--
作者：
Blazer, D;Hybels, C;Hanlon, JT
目的：在过去的15年中，镇静剂、催眠药和抗焦虑药物的处方有所减少。然而，种族差异还没有在对照分析中得到很好的调查。设计：前瞻性队列研究。背景和参与者：作者分析了一个以社区为基础的老年人双种族队列（基线时n = 4000）的数据，随访10年，以确定1986年至1996年期间与这些药物使用相关的社会人口统计学和健康特征。主要结局指标：通过对北卡罗来纳州皮埃蒙特地区的黑人和白人社区老年人进行为期10年的四次面对面访谈，获得了有关镇静、催眠和抗焦虑药物使用以及人口统计学和健康特征的信息。进行描述性统计。最后的模型采用逻辑回归。结果：1986年共有13.3%的受试者服用这些药物，尽管队列年龄增长10岁，但1996年使用频率仅下降到11.8%。基线使用的相关因素是女性性别、白人、抑郁症状、自我评价健康状况不佳、身体功能受损和卫生服务使用情况。这些相关性在调查的后续三波中都持续存在。在1996年的对照分析中，白人使用这些药物的几率是4.70。结论：尽管近年来一般人群中镇静、催眠和抗焦虑药物的使用总体下降，但在本调查的10年期间，一个老龄化队列继续以高于一般人群的频率使用这些药物，并且没有显示出使用的显著下降。与健康状况无关的因素，特别是白人，是在随访期间使用的最强相关因素之一。
OBJECTIVES: Prescriptions of sedatives, hypnotics, and antianxiety medications have decreased over the past 15 years. However, racial differences have not been well investigated in controlled analyses.DESIGN: A prospective cohort study.SETTINGS AND PARTICIPANTS: The authors analyzed data from a community-based, biracial cohort of older adults (n = 4000 at baseline) followed for 10 years to determine sociodemographic and health characteristics associated with the use of these medications between 1986 and 1996.MAIN OUTCOME MEASURES: Information about sedative, hypnotic, and antianxiety medication use and demographic and health characteristics was obtained from a race-stratified, probability-based sample of black and white community-dwelling older adults in the Piedmont region of North Carolina during four in-person interviews spanning 10 years. Descriptive statistics were calculated. Logistic regression was used for the final models.RESULTS: A total of 13.3% of the subjects were taking these medications in 1986, with the frequency of use declining only to 11.8% in 1996 despite the cohort aging 10 years. Correlates of use at baseline were female gender, white race, depressive symptoms, poor self-rated health, impaired physical function, and health services use. These correlates persisted for each of the three follow-up waves of the survey. In 1996, the odds for being white and using these medications was 4.70 in controlled analyses.CONCLUSIONS: Despite the overall decline in the use of sedative, hypnotics, and antianxiety agents in the general population in recent years, over the 10 years of this survey, an aging cohort continued to use these medications at a frequency greater than the general population and did not demonstrate a significant decline in use. Factors unrelated to health status, specifically being white, were among the strongest correlates of use throughout the years of follow-up.