Daily effects of air pollutants and pollen types on asthma and COPD hospital emergency visits in the industrial and Mediterranean Spanish city of Cartagena
Daily effects of air pollutants and pollen types on asthma and COPD hospital emergency visits in the industrial and Mediterranean Spanish city of Cartagena
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DOI：
10.1016/j.aller.2011.05.012
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发表时间：
2012-07-01
影响因子：
1.8
通讯作者：
Navarro, C.
中科院分区：
文献类型：
--
作者：
Cirera, L.;Garcia-Marcos, L.;Navarro, C.
背景：在对哮喘和慢性阻塞性肺疾病（COPD）的医院急诊室（ER）就诊与单一空气污染物的时间序列研究中发现的关联缺乏一致性。空气污染混合物中空气过敏原的呼吸效应尚未得到很好的确定。不同空气传播花粉类型与某些呼吸道疾病的非线性关系也已被描述。我们的目的是研究1995-1998年期间主要空气污染物和空气过敏原花粉对西班牙工业和地中海城市卡塔赫纳哮喘和慢性阻塞性肺病医院急诊就诊的短期影响。方法：考虑延迟效应并根据长期趋势、季节性、天气条件、假期和流感通知进行调整，使用广义加性模型的泊松回归分析了哮喘和COPD就诊与硫和二氧化氮（SO2和NO2）、总悬浮颗粒（TSP）、臭氧（O-3）和主要致敏空气花粉类型的平均水平之间的关系。结果：多污染物模型显示出类似的相对风险（RR）增加（以%计），每增加10 μ g/m(3) SO2，哮喘和COPD急诊室就诊人数约为5%。同样的一氧化氮增加，哮喘患者的急诊就诊风险为2.6%，COPD患者的急诊就诊风险为3.3%。由于哮喘而到急诊室就诊的人数与荨麻科和禾本科水平均呈正相关，但并没有实质性地改变之前的百分比。结论：空气中SO2和NO2水平与因哮喘和COPD就诊的风险显著增加有关。禾科和荨麻科花粉的加入并未改变这种关联。(c) 2011年封盖。Elsevier Espana， S.L.出版，版权所有。
Background: Associations found in time-series studies on hospital emergency room (ER) visits due to asthma and chronic obstructive pulmonary disease (COPD) with single air pollutants show some lack of consistency. The respiratory effects of aeroallergens in the air pollution mix are not well established. Non-linear relationships of different airborne pollen types with certain respiratory diseases have also been described. We aim to study the short-term effects of major air pollutants and aeroallergen pollen on asthma and COPD hospital ER visits in the industrial and Mediterranean Spanish city of Cartagena during 1995-1998.Methods: The association of asthma and COPD to ER visits with mean levels of sulphur and nitrogen dioxides (SO2 and NO2), total suspended particles (TSP), ozone (O-3), and the main allergenic airborne pollen types were analysed using Poisson regression with Generalised Additive Models, taking into account delayed effects and adjusting for long-term trends, seasonality, weather conditions, holidays and flu notifications.Results: Multipollutant models showed a similar relative risk (RR) increase (in %), of around 5% in asthma and COPD ER visits per 10 mu g/m(3) SO2 increments. The risk of an ER visit for the same NO2 increment was 2.6% for asthma and 3.3% for COPD. Visits to the ER due to asthma showed a positive increase with both Urticaceae and Poaceae levels, but did not substantially modify the previous percentages.Conclusions: Air levels of SO2 and NO2 were associated with a substantial increased risk in ER visits due to asthma and COPD. The inclusion of Poaceae and Urticaceae pollen did not alter that association. (C) 2011 SEICAP. Published by Elsevier Espana, S.L. All rights reserved.