Prevention of type 2 diabetes mellitus in women with previous gestational diabetes mellitus.
Prevention of type 2 diabetes mellitus in women with previous gestational diabetes mellitus.
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DOI：
10.3904/kjim.2016.203
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发表时间：
2017-01
期刊：
影响因子：
--
通讯作者：
Jang HC
中科院分区：
文献类型：
--
作者：
Moon JH;Kwak SH;Jang HC
妊娠糖尿病 (GDM) 被定义为在怀孕期间出现或首次识别的任何程度的葡萄糖不耐受，其特征是怀孕期间 β 细胞对胰岛素反应的潜在母体缺陷。与没有 GDM 的女性相比，有 GDM 病史的女性患产后糖尿病的风险高出 7 倍以上。已确定产后糖尿病的各种危险因素，包括母亲年龄、妊娠期血糖水平、糖尿病家族史、孕前和产后体重指数、饮食模式、体力活动和母乳喂养。基因研究表明，GDM 与 2 型糖尿病有共同的基因变异。许多生活方式干预试验旨在改善可改变的危险因素，包括饮食、运动和母乳喂养，成功降低了产后糖尿病、体重滞留和其他肥胖相关疾病的发生率。本综述总结了以往关于产后糖尿病发病率和危险因素的研究结果，并讨论了最近试图预防产后糖尿病的生活方式干预试验。
Gestational diabetes mellitus (GDM), defined as any degree of glucose intolerance with onset or first recognition during pregnancy, is characterized by underlying maternal defects in the β-cell response to insulin during pregnancy. Women with a previous history of GDM have a greater than 7-fold higher risk of developing postpartum diabetes compared with women without GDM. Various risk factors for postpartum diabetes have been identified, including maternal age, glucose levels in pregnancy, family history of diabetes, pre-pregnancy and postpartum body mass index, dietary patterns, physical activity, and breastfeeding. Genetic studies revealed that GDM shares common genetic variants with type 2 diabetes. A number of lifestyle interventional trials that aimed to ameliorate modifiable risk factors, including diet, exercise, and breastfeeding, succeeded in reducing the incidence of postpartum diabetes, weight retention, and other obesity-related morbidities. The present review summarizes the findings of previous studies on the incidence and risk factors of postpartum diabetes and discusses recent lifestyle interventional trials that attempted to prevent postpartum diabetes.
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影响因子：
39
作者：
Bao, Wei;Tobias, Deirdre K.;Bowers, Katherine;Chavarro, Jorge;Vaag, Allan;Grunnet, Louise Groth;Strom, Marin;Mills, James;Liu, Aiyi;Kiely, Michele;Zhang, Cuilin
通讯作者：
Zhang, Cuilin
DOI：
10.1016/0002-9378(93)90358-p
发表时间：
1993-04-01
影响因子：
9.8
作者：
COUSTAN, DR;CARPENTER, MW;CARR, SR
通讯作者：
CARR, SR
影响因子：
8.2
作者：
Cho, Y. M.;Kim, T. H.;Jang, H. C.
通讯作者：
Jang, H. C.
影响因子：
3.5
作者：
Bennett, Wendy L.;Ennen, Christopher S.;Clark, Jeanne M.
通讯作者：
Clark, Jeanne M.
影响因子：
3.5
作者：
DAMM, P;KUHL, C;MOLSTEDPEDERSEN, L
通讯作者：
MOLSTEDPEDERSEN, L