Optical imaging of cell membrane potential changes induced by applied electric fields.
Optical imaging of cell membrane potential changes induced by applied electric fields.
复制标题
施加电场引起的细胞膜电位变化的光学成像。
DOI：
10.1016/s0006-3495(86)83467-1
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发表时间：
1986
影响因子：
3.4
通讯作者：
Webb,WW
中科院分区：
文献类型：
--
作者：
Gross,D;Loew,LM;Webb,WW
我们报告了通过施加外部电场在非兴奋性细胞中诱导的跨膜电位变化的空间分布的首次成像。这些变化通过细胞质膜中掺入的电荷转移电位染料的荧光强度来指示，并通过数字增强视频显微镜进行测量。
We report the first imaging of the spatial distributions of transmembrane potential changes induced in nonexcitable cells by applied external electric fields. These changes are indicated by the fluorescence intensity of a charge-shift potentiometric dye incorporated in the cell plasma membrane and measured by digital intensified video microscopy.