[Effect of puerarin on cerebral blood flow in dogs].
[Effect of puerarin on cerebral blood flow in dogs].
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发表时间：
1995-09
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影响因子：
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通讯作者：
L. Chen;Q. Chai;A. Zhao;X. Chai
中科院分区：
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作者：
L. Chen;Q. Chai;A. Zhao;X. Chai
用脉动多普勒血流仪和经颅多普勒系统同时测定麻醉犬左颅内外动脉的血流动力学。小剂量葛根素(50 mg/kg，iv)不改变脑灌流压，但降低大脑中动脉和大脑前动脉的血流速度。颅内动脉扩张，球脑血流量增加。
The hemodynamics of left intra- and extracranial arteries was determined by a pulsatile Doppler flowmeter and a transcranial Doppler system simultaneously in anesthetized dogs. Low doses of puerarin (50mg/kg, iv) did not alter the cerebral perfusion pressure, but reduced the flow velocities of both middle cerebral artery and anterior cerebral artery. The globle cerebral blood flow was enhanced due to dilatation of the intracranial arteries.