Association between ozone and hospitalization for acute respiratory diseases in children less than 2 years of age

Association between ozone and hospitalization for acute respiratory diseases in children less than 2 years of age
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DOI:
10.1093/aje/153.5.444
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发表时间:
2001-03-01
影响因子:
5
通讯作者:
Krewski, D
Krewski, D
中科院分区:
医学2区
文献类型:
--
作者:
Burnett, RT;Smith-Doiron, M;Krewski, D

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为了阐明臭氧暴露对幼儿健康的影响,作者研究了加拿大多伦多1980年至1994年15年间空气污染与2岁以下儿童因急性呼吸道疾病住院之间的关系。每天的入院时间序列进行了调整,以适应一周中的一天,季节和天气的影响。每日因呼吸问题住院率增加35%(95%置信区间:19%,52%)与每日1小时最大臭氧浓度为十亿分之45的5天移动平均值相关,即5月至8月的平均值。在调整其他环境空气污染物或天气变量后,臭氧的影响仍然存在。臭氧与9月至4月期间的住院率无关。夏季的环境臭氧水平应被视为2岁以下儿童呼吸系统疾病的危险因素。
To clarify the health effects of ozone exposure in young children, the authors studied the association between air pollution and hospital admissions for acute respiratory problems in children less than 2 years of age during the 15-year period from 1980 to 1994 in Toronto, Canada. The daily time series of admissions was adjusted for the influences of day of the week, season, and weather. A 35% (95% confidence interval: 19%, 52%) increase in the daily hospitalization rate for respiratory problems was associated with a 5-day moving average of the daily 1-hour maximum ozone concentration of 45 parts per billion, the May-August average value. The ozone effect persisted after adjustment for other ambient air pollutants or weather variables. Ozone was not associated with hospital admissions during the September-April period. Ambient ozone levels in the summertime should be considered a risk factor for respiratory problems in children less than 2 years of age.