Antitumor and immunomodulating activities of the polysaccharide fractions from Artemisia selengensis and Artemisia iwayomogi

Antitumor and immunomodulating activities of the polysaccharide fractions from Artemisia selengensis and Artemisia iwayomogi
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DOI:
10.1007/bf02974179
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发表时间:
1994-01-01
期刊:
Archives of Pharmacal Research (Seoul)
影响因子:
--
通讯作者:
Youn, Hyun Joo
Youn, Hyun Joo
中科院分区:
其他
文献类型:
--
作者:
Koo, Kyoung Ah;Kwak, Jong Hwan;Youn, Hyun Joo

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研究了从赛冷蒿和艾蒿多糖组分中提取的多糖对免疫系统的影响。分别称为ASP1和AlP1的多糖组分可能与脾中的巨噬细胞和淋巴细胞相互作用,在体内和体外增加这些细胞类型的数量。ASP1和AlP1组分也抑制移植瘤细胞的生长并增加抗体的产生。本研究提示ASP1和AlP1组分可能具有免疫调节和抗肿瘤活性。
Effects of the polysaccharide fractions purified from Artemisia selengensis and Artemisia iwayomogi on the immune system was studied. The polysaccharide fractions, respectively called ASP1 and AlP1, may interact with macrophages and lymphocytes in spleen, increasing the population of those cell types in vivo arid in vitro. Both ASP1 and AlP1 fractions also suppress transplanted tumor cell growth and augment antibody production. This study suggests that ASP1 and AlP1 fractions may have immunomodulating and antitumor activities.