Escherichia coli harboring shiga toxin 2 gene variants:: frequency and association with clinical symptoms
Escherichia coli harboring shiga toxin 2 gene variants:: frequency and association with clinical symptoms
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DOI：
10.1086/338115
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发表时间：
2002-01-01
影响因子：
6.4
通讯作者：
Karch, H
中科院分区：
文献类型：
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作者：
Friedrich, AW;Bielaszewska, M;Karch, H
对来自溶血性尿毒症综合征 (HUS) 患者、无 HUS 的腹泻患者或无症状受试者的产志贺毒素 (Stx) 大肠杆菌 (STEC) 进行基因分型，以评估 stx(2) 变异与感染临床表现之间的关联。在 HUS 患者的 268 份 STEC 分离株中未发现 stx(2d) 和 stx(2e)。在从腹泻患者身上分离到的 262 株 STEC 中，在 41 株中发现了 stx(2d)（15.6%；P
Shiga toxin (Stx)-producing Escherichia coli (STEC) from patients with hemolytic-uremic syndrome (HUS), patients with diarrhea without HUS, or asymptomatic subjects were genotyped to assess associations between stx(2) variants and clinical manifestations of infection. Neither stx(2d) nor stx(2e) was found in 268 STEC isolates from patients with HUS. Of 262 STEC isolates from patients with diarrhea, stx(2d) was found in 41 (15.6%; P