Prognostic value of contractile response during high-dose dipyridamole echocardiography test in heart transplant recipients
Prognostic value of contractile response during high-dose dipyridamole echocardiography test in heart transplant recipients
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DOI：
10.1016/s1053-2498(02)01238-x
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发表时间：
2003-05-01
影响因子：
8.9
通讯作者：
Frigerio, M
中科院分区：
文献类型：
--
作者：
Ciliberto, GR;Parodi, O;Frigerio, M
背景：同种异体冠状动脉血管病变（CAV）仍然是限制心脏移植（HTX）后长期生存的主要因素。 CAV 的诊断仍然基于连续冠状动脉造影。在这项研究中，我们评估了高剂量双嘧达莫超声心动图对 HTX 的预后价值。方法：68 名患者在预定的年度冠状动脉造影后 48 小时内接受了双嘧达莫超声心动图检查。冠状动脉同种异体移植血管病变被定义为 CAV 1（在多变量分析中，局灶性或弥漫性狭窄 1 仍然显着（p < 0.0001））。结论：双嘧达莫超声心动图是一种简单的非侵入性测试，在 HTX 后可以识别需要更严格监测的室壁运动改变的患者。
Background: Coronary allograft vasculopathy (CAV) remains a main factor limiting long-term survival after heart transplantation (HTX). The diagnosis of CAV is still based on serial coronary angiography. In this study, we evaluated the prognostic value of high-dose dipyridamole echocardiography in HTX.Methods: Sixty-eight patients underwent dipyridamole echocardiography within 48 hours of their scheduled annual coronary angiography. Coronary allograft vasculopathy was defined as CAV 1 (focal or diffuse stenosis 1 remained significant (p < 0.0001) at multivariate analysis.Conclusions: Dipyridamole echocardiography is a simple, non-invasive test that after HTX may identify patients with altered wall motion who deserve stricter surveillance.