Cytokines as diagnostic markers of pulpal inflammation
Cytokines as diagnostic markers of pulpal inflammation
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DOI：
10.1111/iej.12030
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发表时间：
2013-06-01
影响因子：
5
通讯作者：
Raghupathy, R.
中科院分区：
文献类型：
--
作者：
ElSalhy, M.;Azizieh, F.;Raghupathy, R.
目的检测和比较不可逆性牙髓炎、无症状性龋损和正常牙髓血中细胞因子IL-2、IL-6、IL-8、IL-10、TNF-α和IFN-α的水平。方法使用棉球从牙髓暴露部位获得血液。25个样本来自正常牙齿，40个来自无症状龋齿暴露的牙髓，43个来自不可逆的牙髓炎牙齿。通过高灵敏度ELISA测定细胞因子水平。使用KruskalWallis和MannWhitney U检验对数据进行统计学分析。结果与对照组相比，
Aim To measure and compare the levels of the cytokines IL-2, IL-6, IL-8, IL-10, TNF- and IFN- in pulpal blood from irreversible pulpitis, asymptomatic caries exposure and normal pulps. Methodology Blood was obtained from pulp exposure sites using cotton pellets. Twenty-five samples were obtained from normal teeth, 40 from asymptomatic caries-exposed pulps and 43 from irreversible pulpitis teeth. Cytokine levels were determined by high-sensitivity ELISA. Data were statistically analysed using KruskalWallis and MannWhitney U-tests. Results Significantly higher levels (P