Body Perfusion CT: Technique, Clinical Applications, and Advances
Body Perfusion CT: Technique, Clinical Applications, and Advances
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DOI：
10.1016/j.rcl.2008.11.003
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发表时间：
2009-01-01
影响因子：
1.9
通讯作者：
Sahani, Dushyant V.
中科院分区：
文献类型：
--
作者：
Kambadakone, Avinash R.;Sahani, Dushyant V.
灌注CT自问世以来取得了巨大的进步，并逐渐将其应用范围从研究领域扩展到常规临床护理。这在肿瘤学环境中尤其值得注意，灌注CT正在成为组织表征、风险分层和监测治疗效果的有价值工具，特别是评估对新型靶向治疗的早期反应。CT的最新技术进步为克服受限组织覆盖和辐射剂量问题的最初限制铺平了道路。在本文中，作者回顾了灌注CT的基本原理和技术，并讨论了其在各种肿瘤和非肿瘤的临床应用中的身体成像。
Perfusion CT has made tremendous progress since its inception and is gradually broadening its applications from the research realm into routine clinical care. This has been particularly noteworthy in the oncological setting, where perfusion CT is emerging as a valuable tool in tissue characterization, risk stratification and monitoring treatment effects especially assessing early response to novel targeted therapies. Recent technological advancements in CT have paved ways to overcome the initial limitations of restricted tissue coverage and radiation dose concerns. In this article, the authors review the basic principles and technique of perfusion CT and discuss its various oncologic and non-oncological clinical applications in body imaging.