Body mass index, weight gain, and incident urinary incontinence in middle-aged women
Body mass index, weight gain, and incident urinary incontinence in middle-aged women
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DOI：
10.1097/01.aog.0000270121.15510.57
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发表时间：
2007-08-01
影响因子：
7.2
通讯作者：
Grodstein, Francine
中科院分区：
文献类型：
--
作者：
Townsend, Mary K.;Danforth, Kim N.;Grodstein, Francine
目的：描述中年妇女体重指数（BMI; kg/m2）、体重增加和尿失禁发生率之间的关系。方法：这是一项在护士健康研究II中进行的前瞻性研究。参与者报告了他们18岁时的体重，以及1989年的当前体重和身高;体重在随后的两年一度的问卷调查中更新。从2001年至2003年，在30 982名37至54岁的妇女中发现了至少每月一次的尿失禁事件，这些妇女在2001年没有报告尿失禁。从至少每周一次尿失禁的病例中收集有关尿失禁类型的信息。采用多变量logistic回归模型估计2001年BMI、18岁至2001年体重变化和尿失禁事件之间关联的多变量校正比值比（OR）和95%置信区间（Cls）。
Objective: To describe the relations between body mass index (BMI; kg/m(2)), weight gain, and incident urinary incontinence in middle-aged women.Methods: This was a prospective study in the Nurses' Health Study II. Participants reported their weight at age 18 years, and current weight and height in 1989; weight was updated on subsequent biennial questionnaires. From 2001-2003, incident cases with at least monthly incontinence were identified among 30,982 women aged 37 to 54 years who reported no incontinence in 2001. Information on incontinence type was collected from incident cases with at least weekly incontinence. Multivariable-adjusted odds ratios (ORs) and 95% confidence intervals (Cls) for the associations between BMI in 2001, weight change from age 18 years to 2001, and incident incontinence were estimated using multivariable logistic regression models.Results: Increasingly higher BMI was related to increasing odds of developing incontinence (P for trend