Lectins: endogenous carbohydrate-binding proteins from vertebrate tissues: functional role in recognition processes?
Lectins: endogenous carbohydrate-binding proteins from vertebrate tissues: functional role in recognition processes?
复制标题
凝集素：来自脊椎动物组织的内源性碳水化合物结合蛋白：在识别过程中的功能作用？
DOI：
10.1016/0024-3205(78)90242-4
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发表时间：
1978
期刊：
影响因子：
6.1
通讯作者：
H. Loh
中科院分区：
文献类型：
--
作者：
D. Simpson;D. R. Thorne;H. Loh
本文将尝试对最近报道在多种脊椎动物组织中鉴定“内源性凝集素”（碳水化合物结合蛋白）的文献进行综述。本文将简要介绍细胞黏菌、植物和各种微生物中凝集素的功能。关于来自脊椎动物组织的凝集素的功能信息的缺乏将允许通过类比在更简单的系统中完成的工作来推测与发育过程中细胞间和细胞内识别过程相关的可能功能。将对这些有趣的脊椎动物凝集素的化学和物理性质进行比较。我们还将回顾我们实验室关于哺乳动物大脑中发育调节的碳水化合物结合蛋白的研究。
An attempt will be made to survey the recent literature which reports the identification of “endogenous lectins”, carbohydrate-binding proteins, in a variety of vertebrate tissues. The function of lectins from cellular slime molds, plants and various microorganisms will be briefly reviewed. The paucity of functional information concerning lectins from vertebrate tissues will allow speculation on possible functions which relate to intercellular and intracellular recognition processes in development, by analogy to work done in simpler systems. Comparisons of the chemical and physical properties of these interesting vertebrate lectins will be made. We will also review studies from our laboratory which concern a developmentally regulated carbohydrate-binding protein in mammalian brain.