Autoimmune Inner Ear Disease in Children
Autoimmune Inner Ear Disease in Children
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DOI：
10.1097/mao.0b013e318204ac01
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发表时间：
2011-02-01
影响因子：
2.1
通讯作者：
Sataloff, Robert T.
中科院分区：
文献类型：
--
作者：
Huang, Natalie C.;Sataloff, Robert T.
目的：了解诊断为自身免疫性内耳疾病的儿科患者对治疗的反应。患者：7名儿童表现为感音神经性听力损失，并被诊断为自身免疫性内耳疾病。干预：通过血液检测诊断。使用类固醇和/或细胞毒性药物治疗。主要观察指标：听力测试纯音平均和语音辨别分数的改善。结果：7例患儿中有6例（85.7%）经治疗得到改善，其余患者无可测量的疾病进展。结论：患有自身免疫性内耳疾病的儿童似乎受益于类固醇和/或细胞毒性药物治疗。虽然这些药物在儿科人群中必须谨慎使用，但不应仅仅因为年龄小而拒绝使用。
Objective: To determine the response to treatment of pediatric patients diagnosed with autoimmune inner ear disease.Patients: Seven children who presented with sensorineural hearing loss and were diagnosed with autoimmune inner ear disease.Intervention: Diagnosis through blood testing. Treatment with steroids and/or cytotoxic medication.Main Outcome Measures: Improvement in pure-tone average and speech discrimination scores on audiometric testing.Results: Six of the 7 children (85.7%) improved with treatment, and the remaining patient had no measurable progression of disease.Conclusion: Children with autoimmune inner ear disease seem to benefit from treatment with steroids and/or cytotoxic medication. Although such medications must be used with caution in the pediatric population, they should not be withheld simply because of young age.