Single-center analysis of the inappropriate use of human albumin and nutritional support in hospitalized patients with hypoproteinemia in China.
Single-center analysis of the inappropriate use of human albumin and nutritional support in hospitalized patients with hypoproteinemia in China.
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DOI：
10.1177/0300060520987731
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发表时间：
2021-03
期刊：
影响因子：
--
通讯作者：
Shi T
中科院分区：
文献类型：
--
作者：
Zhang J;Zhang Z;Shi T
本研究通过单中心分析人血白蛋白的临床使用情况和肠内-肠外营养支持情况，为临床合理使用人血白蛋白建立应用标准。对1984例接受人血白蛋白治疗的患者进行回顾性研究，分析人血白蛋白和肠内-肠外营养支持的合理应用。在1984例患者中，发现1044例（52.6%）人血白蛋白使用不合理。不合理应用的主要指征为低蛋白血症（30.0%）和营养支持（21.9%）。胸外科、骨科、神经外科不合理应用最多，分别占18.4%、8.4%、4.2%。1627例（82%）需要营养支持，745例（45.8%）营养支持不合理。此外，694例患者（35.0%）接受人血清白蛋白作为唯一的营养支持来源。应通过临床培训和审批制度的建立，加强人血白蛋白的合理使用，确保用药安全，降低医疗费用，避免医疗资源的浪费。
This study used single-center analysis of human serum albumin clinical usage and enteral-parenteral nutritional support to establish clinical application standards for the rational use of human serum albumin. A total of 1984 patients receiving human serum albumin were enrolled in this retrospective study to analyze the rational application of human serum albumin and enteral-parenteral nutritional support. Among 1984 patients, 1044 (52.6%) were found to have irrational applications for human serum albumin use. Major indications for irrational applications were hypoproteinemia (30.0%) and nutritional support (21.9%). Surgical departments including thoracic surgery, orthopedics, and neurosurgery had the most irrational applications, occupying 18.4%, 8.4%, and 4.2%, respectively. A total of 1627 patients (82%) required nutritional support and 745 (45.8%) had irrational nutritional support. Moreover, 694 patients (35.0%) received human serum albumin as the only source of nutritional support. Clinical training and the establishment of an approval system should be used to enhance the rational use of human serum albumin, ensuring medication safety, reducing medical costs, and avoiding the waste of medical resources.
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DOI：
10.1177/0115426505020003314
发表时间：
2005-06-01
期刊：
Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition
影响因子：
--
作者：
Mendez, Christian M;McClain, Craig J;Marsano, Luis S
通讯作者：
Marsano, Luis S
影响因子：
6.3
作者：
Kondrup, J;Allison, SP;Plauth, M
通讯作者：
Plauth, M
影响因子：
6.3
作者：
Kreymann, K. G.;Berger, M. M.;Spies, C.
通讯作者：
Spies, C.
影响因子：
3.4
作者：
McClave, Stephen A.;Taylor, Beth E.;Compher, Charlene
通讯作者：
Compher, Charlene
影响因子：
1.3
作者：
Katalinic, Lea;Premuzic, Vedran;Jelakovic, Bojan
通讯作者：
Jelakovic, Bojan