The inter-visit variability of retinal blood flow velocity measurements using retinal function imager (RFI)
The inter-visit variability of retinal blood flow velocity measurements using retinal function imager (RFI)
复制标题
使用视网膜功能成像仪 (RFI) 测量视网膜血流速度的访问间变异性
DOI：
10.1186/s40662-018-0124-z
复制
发表时间：
2018-12-04
期刊：
影响因子：
4.2
通讯作者：
Yuan, Jin
中科院分区：
文献类型：
--
作者：
Deng, Yuqing;Li, Meng;Yuan, Jin
应用视网膜功能成像仪(RFI)测定健康青年受试者视网膜血流速度(BFV)的来访变异性。中心凹中心面积为7.3mm2× 7.3mm2(设置：35度)，分别于两天内重复测量视网膜小动脉和小静脉的BFV。结果初诊时小动脉和小静脉的平均血流速度分别为3.6 ± 0.8 mm/S和3.0 ± 0.7 mm/S，与复诊时的平均血流速度(分别为3.5 ± 0.8 mm/S和3.0 ± 0.7 mm/S，P>； 0.0 5)比较，差异无统计学意义。微动脉和小静脉血流速度的变异系数分别为0.72和0.67，变异系数分别为10.8%和11.0%。结论大视野视网膜功能成像仪(RFI)的访视间变异良好，与文献报道的访内变异和眼间变异相当。
BackgroundTo determine the inter-visit variability of retinal blood flow velocities (BFVs) using a retinal function imager (RFI) in healthy young subjects.MethodsTwenty eyes of 20 healthy young subjects were enrolled. RFI imaging was performed to obtain the BFVs in retinal arterioles and venules in a field measuring 7.3 × 7.3 mm2(setting: 35 degrees) centered on the fovea, and repeated measurements were obtained on two separate days. The inter-visit variability of BFVs was assessed by the concordance correlation coefficient (CCC) and coefficient of variance (CV).ResultsAt the first visit, the mean BFV was 3.6 ± 0.8 mm/s and 3.0 ± 0.7 mm/s in arterioles and venules, respectively, which were not significantly different from those at the second visit (the BFV of arterioles was 3.5 ± 0.8 mm/s, and the BFV of venules was 3.0 ± 0.7 mm/s,P> 0.05, respectively). The CCC was 0.72 in the BFVs of arterioles and 0.67 in venules, and the CV was 10.8% in the BFVs of arterioles and 11.0% in venules.ConclusionThe inter-visit variability using the retinal function imager (RFI) with a large field of view appeared to be good and comparable to previously reported intra-visit and inter-eye variability.