OCCUPATION AND BLADDER-CANCER IN SPAIN - A MULTI-CENTRE CASE-CONTROL STUDY
OCCUPATION AND BLADDER-CANCER IN SPAIN - A MULTI-CENTRE CASE-CONTROL STUDY
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DOI：
10.1093/ije/18.3.569
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发表时间：
1989-09-01
影响因子：
7.7
通讯作者：
NEBOT, M
中科院分区：
文献类型：
--
作者：
GONZALEZ, CA;LOPEZABENTE, G;NEBOT, M
在西班牙的四个地区进行了一项关于膀胱癌的病例对照研究。这项研究包括497例患者(438名男性和59名女性)，583名医院对照组和530名按性别、年龄和居住地匹配的人群对照组。本文报告了职业史分析的结果。在男性中，纺织工人(OR=1.97，95%CL 1.2~3.3)、机械和维修工人(OR=1.86，95%CL 1.2~2.8)、印刷业工人(OR=2.06，95%CL 1.0~4.3)和管理人员(OR=2.03，95%CL 1.2~3.5)患膀胱癌的风险增加。在25岁之前和1960年之前首次受雇于纺织业的人中，风险最高。在机械师中，25岁以后、1960年以后开始工作的人风险最高。同时受雇于高危职业之一的吸烟者的OR为7.82(95%CL 4.4-14.0)，这与联合暴露于烟草和职业危害的乘数效应相一致。
A case-control study on bladder cancer was carried out in four regions of Spain. The study included 497 cases (438 males and 59 females), 583 hospital controls and 530 population controls matched by sex, age and residence. The present paper reports the results of the analyses on occupational history. Among men, an increased risk of bladder cancer was found for textile workers (OR = 1.97, 95% CL 1.2-3.3), mechanics and maintenance workers (OR = 1.86, 95% CL 1.2-2.8), workers in the printing industry (OR = 2.06, 95% CL 1.0-4.3) and for managers (OR = 2.03, 95% CL 1.2-3.5). The risk was highest among those first employed in the textile industry before the age of 25 and prior to 1960. Among mechanics the risk was highest for those who started after the age of 25 and later than 1960. The OR for smokers who had also been employed in one of the high risk occupations was 7.82 (95% CL 4.4-14.0) which is compatible witha multiplicative effect of joint exposure to tobacco and occupational hazards.