BODY MASS INDEX IS RELATED TO AUTONOMIC NERVOUS SYSTEM ACTIVITY AS MEASURED BY HEART RATE VARIABILITY-A REPLICATION USING SHORT TERM MEASUREMENTS
BODY MASS INDEX IS RELATED TO AUTONOMIC NERVOUS SYSTEM ACTIVITY AS MEASURED BY HEART RATE VARIABILITY-A REPLICATION USING SHORT TERM MEASUREMENTS
复制标题
DOI：
10.1007/s12603-014-0022-6
复制
发表时间：
2014-03-01
影响因子：
5.8
通讯作者：
Thayer, J. F.
中科院分区：
文献类型：
--
作者：
Koenig, J.;Jarczok, M. N.;Thayer, J. F.
目的：目前的分析是对以前研究结果的复制，首次证明了健康非肥胖成年人的体重指数（BMI）和自主神经系统（ANS）活动（通过心率变异性（HRV）测量）之间的相关性。设计：共有59名明显健康的男性（M）和女性（F）个体（M/F = 15/44）被纳入试验。用于分析的HRV数据来自5分钟的基线记录，而受试者坐在舒适的椅子上。测量受试者的身体指标（体重和身高），并根据常规计算方法（kg/m2）获得BMI。结果：BMI与HRV的pNN 50和RMSSD分量呈负相关。仅在pNN 50组分分析中，分层组（BMI 25）之间存在统计学显著性差异。pNN 50组分和RMSSD与心脏迷走神经影响密切相关，因此代表副交感神经活动。结论：目前的数据支持先前的发现，即交感神经-迷走神经平衡与非肥胖健康个体的BMI相关，为迷走神经在调节人类机体的能量消耗中的突出作用提供了证据。此外，这种关系可以在5分钟长度的HRV的短期记录中观察到。
Objectives: The present analysis is a replication of previous findings presenting first evidence of an association between body mass index (BMI) and autonomic nervous system (ANS) activity as measured by heart rate variability (HRV), in healthy non-obese adults. Design: A total of fifty-nine apparently healthy male (M) and female (F) individuals (M/F = 15/44) were included in the trial. HRV data for analysis was derived from 5 minutes of baseline recordings, while the subject was sitting on a comfortable chair. Subjects' body measures (weight and height) were taken and BMI was obtained according to common calculation (kg/m(2)). Results: BMI was inversely related to pNN50 and RMSSD components of HRV. Statistically significant differences between stratified groups (BMI25) only occurred for analysis of pNN50 components. The pNN50 components and RMSSD are strongly associated with cardiac vagal influence, and thus represents parasympathetic activity. Conclusions: The present data supports previous findings, that sympatho-vagal balance is related to BMI in non-obese, healthy individuals, providing evidence for a prominent role of the vagus nerve in the modulation of the energy expenditure of the human organism. Furthermore, this relation can be observed in short term recordings of HRV of 5 minutes in length.