Detection of human papillomavirus deoxyribonucleic acid by filter in situ hybridization during pregnancy
Detection of human papillomavirus deoxyribonucleic acid by filter in situ hybridization during pregnancy
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妊娠期滤光片原位杂交检测人乳头瘤病毒脱氧核糖核酸
DOI：
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发表时间：
1989
影响因子：
12.7
通讯作者：
I. Endrödi
中科院分区：
文献类型：
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作者：
J. Czeglédy;L. Gergely;I. Endrödi
从101名健康孕妇（49名妊娠期超过20周，52名妊娠期不到20周）和108名健康非孕妇中采集的样本进行了人乳头瘤病毒（HPV）类型检测。使用6、11、16和18种HPV DNA探针，通过滤膜原位杂交（FISH）检测从宫颈刮下的3 - 5 x 105个脱落细胞。35名孕妇（34.6%）有HPV DNA存在的证据：11.8%（12/101）HPV 6; 7.9%（8/101）HPV 11; 8.9%（9/101）HPV 16;和5.9%（6/101）HPV 18阳性。在20.4%（22/108）的非妊娠女性中检测到HPV DNA。
Samples taken from 101 healthy pregnant women (49 over and 52 under the 20‐week gestational period) and 108 healthy nonpregnant women were tested for human papillomavirus (HPV) types. Using 6, 11, 16, and 18 HPV DNA probes, 3‐5 x 105 exfoliated cells scraped from the cervix were tested by filter in situ hybridization (FISH). Thirty‐five of the pregnant women (34.6%) had evidence of the presence of HPV DNA: with 11.8% (12/101) HPV 6; 7.9% (8/101) HPV 11; 8.9% (9/101) HPV 16; and 5.9% (6/101) HPV 18 positivity. HPV DNA was detected in 20.4% (22/108) of the non‐pregnant women.
从疣状表皮发育不良患者中分离人乳头瘤病毒：人泌尿生殖肿瘤中存在相关病毒 DNA 基因组。
DOI：
10.1073/pnas.79.14.4437
发表时间：
1982
影响因子：
11.1
作者：
Green,M;Brackmann,KH;Sanders,PR;Loewenstein,PM;Freel,JH;Eisinger,M;Switlyk,SA
通讯作者：
Switlyk,SA