The right drugs at the right time for the right patient: the MD Anderson precision oncology decision support platform.
The right drugs at the right time for the right patient: the MD Anderson precision oncology decision support platform.
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DOI:
10.1016/j.drudis.2015.05.013
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发表时间:
2015-12
影响因子:
7.4
通讯作者:
Meric-Bernstam F
中科院分区:
文献类型:
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作者:
Johnson A;Zeng J;Bailey AM;Holla V;Litzenburger B;Lara-Guerra H;Mills GB;Mendelsohn J;Shaw KR;Meric-Bernstam F
The development of resources for clinical interpretation of cancer-associated genetic alterations has significantly lagged behind the technical developments enabling their detection in a time-and cost-efficient manner. The lack of scientific and informatics decision support for oncologists can lead to no action being taken or suboptimal therapeutic choices being made, which could affect the clinical outcome of a patient as well as convoluting research findings from clinical trials. In this article, we describe the precision oncology decision support (PODS) platform developed within The Sheikh Khalifa Bin Zayed Al Nahyan Institute for Personalized Cancer Therapy (IPCT) at MD Anderson Cancer Center; the platform aims to bridge the gap between molecular alteration detection and identification of appropriate treatments.
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影响因子:
1.9
作者:
Huser V;Sincan M;Cimino JJ
通讯作者:
Cimino JJ
影响因子:
4.1
作者:
MacConaill, Laura E.;Garcia, Elizabeth;Lindeman, Neal I.
通讯作者:
Lindeman, Neal I.
影响因子:
28.2
作者:
Bose R;Kavuri SM;Searleman AC;Shen W;Shen D;Koboldt DC;Monsey J;Goel N;Aronson AB;Li S;Ma CX;Ding L;Mardis ER;Ellis MJ
通讯作者:
Ellis MJ
影响因子:
9.3
作者:
Chen K;Meric-Bernstam F;Zhao H;Zhang Q;Ezzeddine N;Tang LY;Qi Y;Mao Y;Chen T;Chong Z;Zhou W;Zheng X;Johnson A;Aldape KD;Routbort MJ;Luthra R;Kopetz S;Davies MA;de Groot J;Moulder S;Vinod R;Farhangfar CJ;Shaw KM;Mendelsohn J;Mills GB;Eterovic AK
通讯作者:
Eterovic AK
影响因子:
82.9
作者:
通讯作者:
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