One-year follow-up results of the 1985-1986 National Heart, Lung, and Blood Institute's Percutaneous Transluminal Coronary Angioplasty Registry.
One-year follow-up results of the 1985-1986 National Heart, Lung, and Blood Institute's Percutaneous Transluminal Coronary Angioplasty Registry.
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DOI：
10.1161/01.cir.80.3.421
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发表时间：
1989-09
期刊：
影响因子：
37.8
通讯作者：
K. Detre;R. Holubkov;S. Kelsey;M. Bourassa;David Williams;David Holmes;G. Dorros;D. Faxon;Richard Myler;Kenneth Kent;Michael Cowley;Richard Cannon;Thomas Robertson
中科院分区：
文献类型：
--
作者：
K. Detre;R. Holubkov;S. Kelsey;M. Bourassa;David Williams;David Holmes;G. Dorros;D. Faxon;Richard Myler;Kenneth Kent;Michael Cowley;Richard Cannon;Thomas Robertson
在1985-1986年经皮腔内冠状动脉成形术登记的1801例患者中，1年总死亡率为3.2%，1年心肌梗死发生率为7.2%，1年冠状动脉搭桥术发生率为13.2%。在78%的所有病变均成功扩张且无重大手术并发症（成功患者）的队列中，相应的发生率分别为1.9%、2.6%和6.4%。近20%的死亡、40%的梗死和25%的搭桥手术发生在一小部分（6.8%）持续术中闭塞的患者中。多血管病变患者的事件发生率高于单血管病变患者。1年后，无论最初的成功与否，大约四分之三的存活患者报告无心绞痛状态。然而，与成功的患者相比，不成功的患者更频繁地进行介入搭桥手术（42%对6%）以达到无症状状态。1985-1986年与1977-1981年的1年事件发生率比较表明，所有重大不幸事件都有所减少。在控制了1985-1986年登记患者中更广泛的疾病后，这些减少变得明显。相比之下，重复血管成形术的使用增加了50%。我们的结论是，在1985-1986登记队列中报告的改善的初步结果在1年随访中保持不变。
In 1,801 patients in the 1985-1986 Percutaneous Transluminal Coronary Angioplasty Registry, overall 1-year mortality was 3.2%, the 1-year myocardial infarction rate was 7.2%, and the 1-year coronary artery bypass surgery rate was 13.2%. In the 78% of the cohort with all lesions successfully dilated and without major procedural complications (successful patients), the corresponding rates were 1.9%, 2.6%, and 6.4%. Nearly 20% of all deaths, 40% of all infarctions, and 25% of all bypass operations occurred in the small subset of patients (6.8%) who sustained periprocedural occlusion. Event rates were higher in patients with multivessel disease than in those with one-vessel disease. At 1 year, angina-free status was reported by approximately three fourths of all surviving patients, regardless of initial success. However, compared with successful patients, unsuccessful patients underwent intervening bypass surgery (42% vs. 6%) to achieve asymptomatic status more frequently. Comparison of the 1-year event rates in the 1985-1986 registry with those in the 1977-1981 registry indicated reductions in all major untoward events. These reductions became apparent after controlling for the more extensive disease of the 1985-1986 registry patients. In contrast, use of repeat angioplasty has increased by 50%. We conclude that the improved initial results reported in the 1985-1986 registry cohort were maintained at 1-year follow-up.