Complicated vs uncomplicated mild traumatic brain injury: Acute neuropsychological outcome
Complicated vs uncomplicated mild traumatic brain injury: Acute neuropsychological outcome
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DOI：
10.1080/02699050601082156
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发表时间：
2006-12-01
期刊：
影响因子：
1.9
通讯作者：
Iverson, Grant L.
中科院分区：
文献类型：
--
作者：
Iverson, Grant L.
主要目的：本研究的目的是仔细研究复杂性与非复杂性轻度颅脑损伤(MTBI)对急性神经心理结局的影响。研究设计：研究对象来源于创伤档案数据库。这是一项回顾性配对设计。方法和步骤：所有患者都是通过颅脑损伤创伤服务的临床路径来查看的。所有患者必须在受伤后两周内接受过受伤当天的CT扫描，并完成了一系列少量的神经心理测试。根据CT扫描正常或异常将患者分为两组。然后，患者在年龄、教育程度、性别和受伤方式(例如，车祸、摔倒或袭击)上进行仔细匹配。最终样本包括100名患者，每组50人。主要结果和结果：合并MTBI的患者在一些神经心理测试中表现明显较差。结论：MTBI患者恢复较慢或不能完全恢复的原因尚不清楚。可见的结构性脑损伤增加了缓慢和不完全恢复的风险，但肯定不能解释大多数患者的预后好坏。
Primary objective: The purpose of this study was to carefully examine the effects of a complicated vs uncomplicated mild traumatic brain injury (MTBI) on acute neuropsychological outcome. Research design: Participants were derived from an archival trauma database. This is a retrospective matched groups design.Methods and procedures: All patients were seen through a Head Injury Trauma Service clinical pathway. To be included, all patients must have undergone a day-of-injury CT scan and completed a small battery of neuropsychological tests within 2 weeks of injury. Patients were sorted into two groups on the basis of having a normal or abnormal CT scan. Patients were then carefully matched on age, education, gender and mode of injury (e.g. car accident, fall or assault). The final sample consisted of 100 patients, with 50 in each group.Main outcomes and results: The patients with complicated MTBIs performed significantly more poorly on some of the neuropsychological tests. However, the effect sizes were small or medium and the two groups could not be differentiated using logistic regression analysis.Conclusions: The reasons why people recover slowly or fail to recover fully from MTBIs remain poorly understood. Visible structural brain damage carries increased risk for slow and incomplete recovery, but certainly does not provide an explanation for good or poor outcome in the majority of patients.