Rate of synthesis along replicons of different kinds of mammalian cells.
Rate of synthesis along replicons of different kinds of mammalian cells.
复制标题
不同种类哺乳动物细胞复制子的合成率。
DOI：
10.1016/0022-2836(69)90306-4
复制
发表时间：
1969
影响因子：
5.6
通讯作者：
A. Schaefer
中科院分区：
文献类型：
--
作者：
R. B. Painter;A. Schaefer
使用先前发表的方法（Painter，Jermany和Rasmussen，1966）的改编，对五种哺乳动物细胞中的DNA链增长率进行了估计。这些速率从一种细胞类型到另一种细胞类型变化相对较小，即使这些细胞完全复制其DNA所需的时间差异很大。因此，哺乳动物细胞DNA合成的总体速率似乎主要受操作中的复制子数量的调节，并且仅轻微地（如果有的话）受沿着复制子的链生长速率的差异的影响。
Estimates were made of the rates of DNA chain growth in five kinds of mammalian cells, using an adaptation of a previously published method (Painter, Jermany & Rasmussen, 1966). These rates vary relatively little from one cell type to another even though the times required for these cells completely to replicate their DNA vary considerably. Therefore, the over-all rate of mammalian cell DNA synthesis appears to be regulated primarily by the number of replicons in operation, and is only slightly, if at all, affected by differences in rate of chain growth along replicons.