The neuronal mechanisms of respiratory rhythm generation
The neuronal mechanisms of respiratory rhythm generation
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DOI：
10.1016/s0959-4388(96)80033-x
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发表时间：
1996-12
影响因子：
5.7
通讯作者：
J. Ramirez;D. Richter
中科院分区：
文献类型：
--
作者：
J. Ramirez;D. Richter
新的，改进的体内和体外方法已经导致更好地理解产生呼吸节律的机制，这取决于网络和内在膜特性之间的复杂相互作用。延髓腹外侧的前波青格复合体对呼吸节律的产生特别重要。这个复合体可以单独研究，它包含所有已知类型的呼吸神经元，现在可以进行详细的细胞和分子分析。
New, improved in vivo and in vitro approaches have led to a better understanding of the mechanisms that generate respiratory rhythm, which depends on a complex interaction between network and intrinsic membrane properties. The pre-Bötzinger complex in the ventrolateral medulla is particularly important for respiratory rhythm generation. This complex can be studied in isolation, and it contains all the known types of respiratory neurons that are now amenable to detailed cellular and molecular analyses.