Influences of gender in metabolic syndrome and its components among people living with HIV virus using antiretroviral treatment in Hawassa, southern Ethiopia.
Influences of gender in metabolic syndrome and its components among people living with HIV virus using antiretroviral treatment in Hawassa, southern Ethiopia.
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DOI：
10.1186/s13104-016-1953-2
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发表时间：
2016-03-05
影响因子：
1.8
通讯作者：
Tesfaye, Demo Yemane
中科院分区：
文献类型：
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作者：
Hirigo, Agete Tadewos;Tesfaye, Demo Yemane
背景技术背景：在埃塞俄比亚，关于性别对使用抗逆转录病毒治疗（ART）的代谢综合征（MetS）患者的影响的数据很少。本研究的目的是评估性别的影响MetS及其组件之间接受ART.METHODS的HIV感染患者：2012年2月至2013年4月进行了横断面研究。收集了185例使用ART的HIV患者的人口统计学、临床和人体测量学特征数据。国际糖尿病联盟（IDF）和美国国家胆固醇教育计划：成人治疗（US NCEP-ATP）面板III标准被用来定义MetS.RESULT：共招募了185（36.8%男性和63.2%女性）参与者在这项研究中。MetS的总患病率分别为24.3%和17.8%，采用IDF和NCEP-ATP标准诊断。使用IDF标准，女性的MetS显著高于男性（33.3 vs. 8.8%; p = 40岁与使用NCEP-ATP的MetS显著相关：UOR和AOR（95% CI）为3.1（1.2-8.3）和3.8（1-13.70）。包括MetS成分在内的综合医疗护理方法是最大限度地降低HIV患者发生心血管疾病风险的重要手段。感染者使用抗逆转录病毒疗法。
BACKGROUND: Data regarding the influences of gender in metabolic syndrome (MetS) among patients using antiretroviral treatment (ART) in Ethiopia is scarce. The aim of this study was to assess the influences of gender in MetS and its components among HIV-infected patients receiving ART.METHODS: A cross-sectional study was conducted between February 2012 and April 2013. Data on demographic, clinical and anthropometric characteristics were collected from 185 HIV patients using ART. Glucose and lipid profiles were measured from overnight fast blood. The International Diabetes Federation (IDF) and United States national cholesterol education program: adult treatment (US NCEP-ATP) panel III criteria were used to define MetS.RESULT: A total number of 185 (36.8% males and 63.2% females) participants were recruited in this study. The overall prevalence of MetS was 24.3 and 17.8%, diagnosed using IDF and NCEP-ATP criteria respectively. Using IDF criteria, MetS was significantly higher in females compared to males (33.3 vs. 8.8%; p = 40 years was significantly associated with MetS using NCEP-ATP: UOR and AOR (95% CI) were 3.1 (1.2-8.3), and 3.8 (1-13.70) respectively.CONCLUSION: Comprehensive medical care approach including with MetS components are a crucial instruments in order to minimize the risk of developing cardiovascular diseases in HIV-infected patients using ART.