Abdominal Visceral Adiposity in the First Trimester Predicts Glucose Intolerance in Later Pregnancy
Abdominal Visceral Adiposity in the First Trimester Predicts Glucose Intolerance in Later Pregnancy
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DOI：
10.2337/dc09-0290
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发表时间：
2009-07-01
期刊：
影响因子：
16.2
通讯作者：
Ray, Joel G.
中科院分区：
文献类型：
--
作者：
Martin, Aisling Mary;Berger, Howard;Ray, Joel G.
OBJECTIVE - To assess whether abdominal adiposity in early pregnancy is associated with a higher risk of glucose intolerance at a later gestational stage.RESEARCH DESIGN AND METHODS - Subcutaneous and visceral fat was measured with ultrasonography at similar to 12 weeks' gestation. A 50-g glucose challenge test (GCT) was performed between 24 and 28 weeks' gestation. The risk of having a positive GCT (>= 7.8 mmol/l) was determined in association with subcutaneous and visceral adipose tissue depths above their respective upper-quartile values relative to their bottom three quartile values.RESULTS - Sixty-two women under-went GCTs. A visceral adipose tissue depth above the upper quartile value was significantly associated With a positive GCT in later pregnancy (adjusted odds ratio 16.9 [95% CI 1.5-194.6]). No associations were seen for subcutaneous adipose tissue.CONCLUSIONS - Measurement of visceral adipose tissue depth in early pregnancy may be associated with glucose intolerance later in pregnancy.
