Inhibition of ferrous-induced lipid peroxidation by dipyridamole, RA-642 and mopidamol in human lung tissue
Inhibition of ferrous-induced lipid peroxidation by dipyridamole, RA-642 and mopidamol in human lung tissue
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DOI：
10.1016/0306-3623(95)02098-5
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发表时间：
1996-07-01
期刊：
影响因子：
--
通讯作者：
delaCuesta, FS
中科院分区：
文献类型：
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作者：
DelaCruz, JP;Olveira, C;delaCuesta, FS
1.亚铁诱导的脂质过氧化作用的体外产生量为5.71倍2。嘧啶衍生物RA-642比双嘧达莫更有效地抑制亚铁诱导的脂质过氧化反应;莫匹哒无影响。所有化合物对大鼠肺组织的抗氧化活性均高于对人肺组织的抗氧化活性。
1. The in vitro production of ferrous induced lipid peroxidation was 5.71 time2. The pyrimido-pyrimidine derivative RA-642 shows a more potent inhibition of ferrous-induced lipid peroxidation than dipyridamole; mopidamol had no effect. All the compounds showed higher antiperoxidative effect in rat than in human lung tissue.