Additional Experience with Dexmedetomidine in Pediatric Patients
Additional Experience with Dexmedetomidine in Pediatric Patients
复制标题
右美托咪定用于儿科患者的其他经验
DOI：
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发表时间：
2003
期刊：
影响因子：
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通讯作者：
P. Russo
中科院分区：
文献类型：
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作者：
J. Tobias;J. Berkenbosch;P. Russo
目的本研究评价右旋美托咪定在机械通气期间镇静以外的临床应用效果。方法对儿科重症监护病房和麻醉后监护病房接受右美托咪定治疗的患儿进行回顾性分析。结果3例患者持续输注右美托咪定，2例患者单次给药(0.5 mg/kg)。在五种临床方案中，右旋美托咪定在两名患者的自主呼吸过程中提供了有效的镇静，一名患者逆转了戒断非法物质的临床体征和症状，另外两名患者有效地治疗了麻醉后出现的神志不清和寒战。结论这些初步数据表明，右美托咪定可能是一种有效的镇静药物，可用于自主呼吸患者的镇静治疗、药物停药治疗和两种常见的麻醉后问题的治疗。
Purpose This study evaluates the efficacy of dexmedetomidine in clinical scenarios other than sedation during mechanical ventilation. Methods We conducted a retrospective chart review and presentation of case series of children in the pediatric intensive care unit and the postanesthesia care unit who received dexmedetomidine. Results Dexmedetomidine was administered by continuous infusion to three patients and as a single bolus dose (0.5 &mgr;g/kg) to two patients. In the five clinical scenarios, dexmedetomidine provided effective sedation during spontaneous ventilation in two patients, reversed the clinical signs and symptoms of withdrawal from illicit substances in one patient, and was effective in the treatment of postanesthesia emergence delirium and shivering in two additional patients. Conclusion These preliminary data suggest that dexmedetomidine may be an effective agent for sedation in spontaneously breathing patients, in the treatment of drug withdrawal, and in the treatment of two common postanesthesia problems.
灵长类蓝斑和可乐定对阿片戒断的影响。
DOI：
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发表时间：
1982
期刊：
The Journal of clinical psychiatry
影响因子：
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作者：
RedmondJr,DE;Huang,YH
通讯作者：
Huang,YH