Potential of membrane-assisted solvent extraction for the determination of phosphoric acid triesters in wastewater samples by liquid chromatography-tandem mass spectrometry
Potential of membrane-assisted solvent extraction for the determination of phosphoric acid triesters in wastewater samples by liquid chromatography-tandem mass spectrometry
复制标题
DOI：
10.1016/j.chroma.2006.03.115
复制
发表时间：
2006-08-18
影响因子：
4.1
通讯作者：
Reemtsma, Thorsten
中科院分区：
文献类型：
--
作者：
Quintana, Jose Benito;Reemtsma, Thorsten
采用膜辅助溶剂萃取（MASE）方法从废水中提取几种非离子有机磷化合物，然后用LC-MS/MS进行测定。该方法是为各种氯化磷酸盐（三氯乙基，三氯丙基）和非氯化磷酸盐（三苯基，三丁基）用作阻燃剂和增塑剂，如三乙基己基和三丁氧基乙基磷酸盐。对提取溶剂、进样量、离子强度、提取温度、提取时间等参数进行了优化。最终方法提供了良好的定量限（1-25 ng L-1）和线性（R-2 > 0.9978）。高浓度下的方法精密度也良好（500 ng L-1水平下的平均RSD为5%），但在较低浓度下降低（20 ng L-1水平下的平均RSD为20%）。在这些化合物的连续LC-MS/MS分析中，MASE产生比SPE更低的基质效应，避免了定量标准加入的需要。当应用于废水样品的比较结果得到使用MASE与内标校准或SPE与标准添加。(c)2006 Elsevier B. V.保留所有权利。
A membrane-assisted solvent extraction (MASE) method is presented for the extraction of several non-ionic organophosphorus chemicals from wastewaters samples followed by LC-MS/MS determination. The method was developed for a variety of chlorinated phosphates (trichloroethyl, tichloropropyl) and non-chlorinated phosphates (triphenyl, tributyl) used as flame retardants and for plasticizers such as triethylhexyl and trisbutoxyethyl phosphate. Parameters such as extracting solvent, sample volume and ionic strength, extraction temperature and time were optimized. The final method provides good quantification limits (1-25 ng L-1) and linearity (R-2 > 0.9978). Method precision was also good at high concentrations (5% mean RSD at the 500 ng L-1 level) but decreased at lower concentrations (20% mean RSD at the 20 ng L-1 level). MASE yields lower matrix effects than SPE in a successive LC-MS/MS analysis of these compounds, avoiding the need for standard addition for quantification. When applied to wastewater samples comparable results were obtained using either MASE with internal standard calibration or SPE with standard addition. (c) 2006 Elsevier B.V. All rights reserved.