Catalytic C-C Cleavage/Alkyne-Carbonyl Metathesis Sequence of Cyclobutanones.
Catalytic C-C Cleavage/Alkyne-Carbonyl Metathesis Sequence of Cyclobutanones.
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DOI：
10.1021/acs.orglett.0c01317
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发表时间：
2020-04
期刊：
影响因子：
5.2
通讯作者：
Jiqiang Gao;Chunhui Liu;Zhongjuan Li;Haotian Liang;Y. Ao;Jinbo Zhao;Yuchao Wang;Yuanqi Wu;Yu Liu
中科院分区：
文献类型：
--
作者：
Jiqiang Gao;Chunhui Liu;Zhongjuan Li;Haotian Liang;Y. Ao;Jinbo Zhao;Yuchao Wang;Yuanqi Wu;Yu Liu
A ring-opening/alkyne-carbonyl metathesis sequence of alkyne-tethered cyclobutanones catalyzed by AgSbF6 is realized for the first time to furnish multisubstituted naphthyl ketones under mild conditions. A range of substrates decorated with various substituents at different positions were all well accommodated. Preliminary mechanistic studies show that silver salt acted as a Lewis acid to facilitate both C-C cleavage of the cyclobutanone moiety and the subsequent metathesis between C═O and C≡C bonds.
