Use of electroacupuncture to accelerate the antidepressant action of selective serotonin reuptake inhibitors: a single-blind, randomised, controlled study.
Use of electroacupuncture to accelerate the antidepressant action of selective serotonin reuptake inhibitors: a single-blind, randomised, controlled study.
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发表时间：
2013-12
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通讯作者：
Z. Zhang;R. Ng;S. Man;J. T. S. Li;W. Wong;H. Wong;D. Wang;M. Wong;A. Tsang;K. Yip;S. Sze
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作者：
Z. Zhang;R. Ng;S. Man;J. T. S. Li;W. Wong;H. Wong;D. Wang;M. Wong;A. Tsang;K. Yip;S. Sze
1.密集颅电针刺激（DCEAS）治疗的患者在17项汉密尔顿抑郁量表评分和临床显著治疗反应方面的下降幅度明显大于假针灸治疗的患者（19.4% vs.8.8%）。2.假针灸和DCEAS对血小板血清素系统都没有影响。3.在选择性5-羟色胺再摄取抑制剂治疗抑郁症的早期阶段，DCEAS可作为一种辅助治疗。4. DCEAS效应的神经生物学机制需要使用神经影像学进行进一步研究。
1. Patients treated with dense cranial electroacupuncture stimulation (DCEAS) had a significantly greater reduction in the 17-item Hamilton Rating Scale for Depression scores and clinically significant response to treatment than those having sham acupuncture (19.4% vs.8.8%). 2. Neither sham acupuncture nor DCEAS had effects on the platelet serotonin system. 3. In the early phase of selective serotonin reuptake inhibitor treatment for depressed patients, DCEAS could be used as an additional therapy. 4. Neurobiological mechanisms responsible for DCEAS effects warrant further investigation using neuroimaging.