The incidence of gastric carcinoma in Asian migrants to the United States and their descendants
The incidence of gastric carcinoma in Asian migrants to the United States and their descendants
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DOI：
10.1023/a:1008849014992
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发表时间：
1999-02-01
影响因子：
2.3
通讯作者：
Weiss, NS
中科院分区：
文献类型：
--
作者：
Kamineni, A;Williams, MA;Weiss, NS
目的：我们研究了在美国的中国人、日本人和菲律宾人胃癌的发病率，以获得关于这种疾病病因的更多信息。年龄、种族和出生地的居民的夏威夷，旧金山弗朗西斯科/奥克兰，西北部的华盛顿谁被诊断为胃癌在1973年至1986年期间，从人口为基础的登记，和一个特殊的表格从1980年人口普查被用来估计的人数年的风险为每一类居民。结果：日裔美国人胃癌的发病率比美国出生的白人高3至6倍，其中在日本出生的人发病率最高。在美国出生的中国人和中国男性移民到美国的比例与白人相似，而中国女性移民的比例是白色美国女性的两倍。无论出生地如何，菲律宾男性的风险仅为美国出生的白色男性的60%，而他们的女性同行的风险与美国出生的白色女性非常相似。日裔美国人和中国女性移民中观察到的高发病率在很大程度上仅限于网站以外的胃cardi.Conclusions：我们的研究结果表明，饮食和其他生活方式之间的差异，不同世代的日裔美国人，和日本居民之间的美国和日本可能提供的线索胃癌的病因超出了贲门。
Objectives: We examined the incidence of gastric carcinoma in Chinese, Japanese, and Filipino residents of the United States to obtain additional information about the etiology of this disease.Methods. The age, race, and birthplace of residents of Hawaii, San Francisco/Oakland, and northwestern Washington who were diagnosed with gastric carcinoma during the period 1973-1986 were obtained from population-based registries, and a special tabulation from the 1980 Census was used to estimate the number of person-years at risk for each category of resident.Results: The incidence of gastric carcinoma in Japanese-Americans was three to six times higher than that of US-born whites, with the highest rates occurring in those persons born in Japan. The rate in US-born Chinese and Chinese men who immigrated to the US was similar to that of whites, whereas the rate in Chinese female migrants was twice that of white American women. Filipino men, regardless of birthplace, were only at 60% the risk of US-born white men, while their female counterparts had a rate very similar to that of US-born white women. The high incidence observed among Japanese-Americans and Chinese female immigrants was largely restricted to sites other than the gastric cardia.Conclusions: Our findings suggest that dietary and other lifestyle differences between the different generations of Japanese-Americans, and between Japanese residents of the US and Japan may provide clues regarding the etiologies of stomach cancers that arise beyond the gastric cardia.