Ultrasensitive QRS made by supramolecular assembly of functionalized cyclodextrins and graphene for the detection of lung cancer VOC biomarkers
Ultrasensitive QRS made by supramolecular assembly of functionalized cyclodextrins and graphene for the detection of lung cancer VOC biomarkers
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DOI：
10.1039/c4tb01041h
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发表时间：
2014-01-01
影响因子：
7
通讯作者：
Feller, Jean-Francois
中科院分区：
文献类型：
--
作者：
Nag, Sananda;Duarte, Lisday;Feller, Jean-Francois
开发了一种新型电子鼻系统，该系统包括官能化β-环糊精包裹的还原氧化石墨烯（RGO）传感器，该传感器具有区分一组挥发性有机化合物的独特能力。用RGO对化学官能化的环糊精进行非共价修饰是通过在必要时使用芘金刚烷作为连接体来进行的，以构建超分子组装体。利用环糊精的选择性化学修饰的原理改变环糊精上的化学官能度。在本研究中，主-客体包合物形成能力和环糊精的可调化学功能性以及石墨烯的高表面积和电导率的组合益处被用于开发一组高度选择性的量子电阻化学气相传感器（QRS），其可以组装在电子鼻中。
A novel electronic nose system comprising functionalized beta-cyclodextrin wrapped reduced graphene oxide (RGO) sensors with distinct ability of discrimination of a set of volatile organic compounds has been developed. Non-covalent modification of chemically functionalized cyclodextrin with RGO is carried out by using pyrene adamantane as a linker wherever necessary, in order to construct a supramolecular assembly. The chemical functionality on cyclodextrin is varied utilising the principle of selective chemical modification of cyclodextrin. In the present study, the combined benefits of the host-guest inclusion complex formation ability and tunable chemical functionality of cyclodextrin, as well as the high surface area and electrical conductivity of graphene, are utilized for the development of a set of highly selective quantum resistive chemical vapour sensors (QRS), which can be assembled in an electronic nose.