Interactions between monogenean parasites and their fish hosts
Interactions between monogenean parasites and their fish hosts
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DOI：
10.1016/s0020-7519(01)00332-0
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发表时间：
2002-03-01
影响因子：
4
通讯作者：
Lindenstrom, T
中科院分区：
文献类型：
--
作者：
Buchmann, K;Lindenstrom, T
寄生虫因素与识别和选择的主机和主机负责接受或拒绝入侵生物的机制进行了评估。寄生虫的感觉结构能够检测不同鱼类之间的差异，这种区分鱼类的能力可能是基于宿主表面的化学和机械刺激。复杂的糖蛋白，蛋白质。碳水化合物和简单分子吸引寄生虫或改变它们的行为。此外，单殖吸虫对宿主的附着依赖于寄生虫中的机械结构和化学因素。这些系统包括前垫、后襻、腺体分泌物和肌肉成分。寄生虫需要获得可被吸收并用于繁殖的适当营养物，并且在这种情况下，寄生虫的最佳生理反应需要来自宿主的信号。宿主的先天性和适应性免疫系统是这个问题的重要因素。研究表明，先天性宿主因子（补体、凝集素、急性期反应物、巨噬细胞）可与单殖吸虫结合并对寄生虫造成严重损害。这些有害产物的靶点不仅是单殖吸虫皮层，而且可能涉及胃皮和腺体。然而，寄生虫的能力，以避免，甚至利用广泛的免疫元素的主机可能是一个重要的球员之间的动态相互作用的主机和单殖吸虫确定主机的特异性。即使是对某种寄生虫易感的鱼类宿主，也能在感染后阶段产生保护性反应。单殖吸虫感染一段时间后，宿主产生适应性和非适应性因子的水平升高，可以解释获得性反应。(C)2002年澳大利亚寄生虫学会由Elsevier Science Ltd.出版，版权所有。
Parasite factors associated with recognition and selection of the host and the mechanisms in the host responsible for acceptance or rejection of the invading organism were evaluated. Sensory structures in parasites are able to detect differences between different fish species and this ability to discern between fishes may be based on both chemical and mechanical stimuli on the host surface. Complex glycoproteins, proteins. carbohydrates and simple molecules attract parasites or modify their behaviour. Furthermore, attachment of the monogenean parasite to a host is dependent on both mechanical structures and chemical factors in the parasite. These systems comprise anterior pads, posterior haptors, gland secretions, and muscular elements. The parasite needs access to appropriate nutrients which can be absorbed and used for reproduction and in this context signals from the host are needed for an optimal physiological response of the parasite. The innate and adaptive immune systems of the host are important elements in this question. Investigations have indicated that innate host factors (complement, lectins, acute phase reactants, macrophages) can bind to monogeneans and elicit severe damage to the parasites. The targets for these hostile products are not only the monogenean tegument, but may involve the gastrodermis and glands. However, the parasite's ability to avoid and even exploit the wide array of immunological elements of the host may be an important player in the dynamic interactions between host and monogenean determining host specificity. Even fish hosts susceptible to a certain parasite show an ability to mount a protective response at post-infection periods. Elevation of the host's production of adaptive and non-adaptive factors following monogenean infections of a certain duration may explain the acquired response. (C) 2002 Australian Society for Parasitology Inc. Published by Elsevier Science Ltd. All rights reserved.