Developmental aspects of maternal-fetal, and infant gut microbiota and implications for long-term health.

Developmental aspects of maternal-fetal, and infant gut microbiota and implications for long-term health.
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DOI:
10.1186/s40748-015-0007-4
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发表时间:
2015
期刊:
Maternal health, neonatology and perinatology
影响因子:
--
通讯作者:
Neu J
Neu J
中科院分区:
其他
文献类型:
--
作者:
Neu J

文献摘要

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人类宿主和微生物之间的早期生命相互作用为未来的健康和疾病奠定了基础。在这篇综述中,将讨论人类微生物组效应的一些关系,因为它们与早产,早产婴儿中观察到的早期疾病以及其他儿童和成人疾病(包括自身免疫,过敏性疾病,肥胖或健康表型)有关。虽然这些领域的数据刚刚开始出现,但本综述将简要总结正在进行的一些关键研究,并对提出重大问题的新兴领域进行推测。
Early life interactions between the human host and microbes set the stage for future health and disease. In this review, some of the relationship of the human microbiome effects will be discussed as they relate to preterm delivery, early life diseases seen in prematurely delivered infants, and other childhood and adult maladies which include autoimmunity, allergic diseases, obesity or a healthy phenotype. Although the data in these areas is just beginning to emerge, this review will provide a brief summary of some of the key research being done and will also speculate on emerging areas where major questions are being raised.