Central nervous system toxicity from cancer therapies

Central nervous system toxicity from cancer therapies
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DOI:
10.1016/j.hoc.2006.09.004
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发表时间:
2006-12-01
影响因子:
2.4
通讯作者:
Wen, Patrick
Wen, Patrick
中科院分区:
医学4区
文献类型:
--
作者:
Schiff, David;Wen, Patrick

文献摘要

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The central nervous system (CNS) is an organ with a unique profile of vulnerability to antineoplastic treatments. In many cases, CNS neurotoxicity is the dose-limiting side effect of treatment for systemic and CNS neoplasms. Novel methods of delivering radiation and chemotherapy agents have led to recognition of new forms of CNS neurotoxicity. In this article, the authors review the most important CNS toxicities of cancer treatment.