Conservation of the molecular structure of yeast phenylalanine transfer RNA in two crystal forms.
Conservation of the molecular structure of yeast phenylalanine transfer RNA in two crystal forms.
复制标题
两种晶体形式的酵母苯丙氨酸转移 RNA 分子结构的保守性。
DOI：
--
复制
发表时间：
1974
影响因子：
11.1
通讯作者：
J. Finch
中科院分区：
文献类型：
--
作者：
A. Klug;J. Robertus;J. Ladner;R. S. Brown;J. Finch
本文比较了我们和他人所获得的酵母tRNA（Phe）单斜晶型和正交晶型的电子密度图。它的结论是，分子结构基本上是相同的，在这两种晶体中，虽然来自地图的模型是不一样的。讨论了这两种分子堆积之间的关系，并提出了在单斜晶系中不存在的正交晶系中的分子间接触可能是通过相邻分子的反密码子的碱基配对而产生的。
A comparison is made between the electron density maps of the monoclinic and orthorhombic crystal forms of yeast tRNA(Phe) which have been obtained respectively by ourselves and by another group. It is concluded that the molecular structures are essentially the same in both crystals, although the models derived from the maps are not the same. The relation between the two molecular packings is discussed, and it is suggested that the intermolecular contact in the orthorhombic form which is not present in the monoclinic form, may arise through base pairing of the anticodons of neighboring molecules.