Defining neuropsychological dysfunction after coronary artery bypass grafting
Defining neuropsychological dysfunction after coronary artery bypass grafting
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DOI：
10.1016/0003-4975(95)01095-5
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发表时间：
1996-05-01
影响因子：
4.6
通讯作者：
Newman, MF
中科院分区：
文献类型：
--
作者：
Mahanna, EP;Blumenthal, JA;Newman, MF
背景。尽管大量文献记录了冠状动脉旁路移植术后认知能力下降的情况，但对于认知障碍的频率和程度几乎没有达成共识。造成这种不一致的一个潜在原因是缺乏评估认知衰退的统一标准。方法。 232 名患者在手术前一天、出院前以及移植后 6 周和 6 个月接受了认知测试。出于比较目的，使用五组不同的标准来定义认知能力下降。结果。关于哪些患者在每个测试期间出现下降的标准之间几乎没有达成一致。出院前下降发生率为66%至15.3%，6周时为34%至1.1%，6个月时为19.4%至3.4%。结论。冠状动脉搭桥术后认知能力下降发生率的巨大差异可归因于定义认知障碍的不同标准。
Background. Despite the large body of literature documenting the presence of cognitive decline after coronary artery bypass grafting, there is little consensus as to the frequency and extent of cognitive impairment. One potential reason for this lack of agreement is the absence of uniform criteria for assessing cognitive decline.Methods. Two hundred thirty-two patients underwent cognitive testing the day before operation and were examined before discharge, and at 6 weeks and 6 months after grafting. For comparative purposes, five different sets of criteria were used to define cognitive decline.Results. There was little agreement between the criteria as to which patients declined at each test period. The incidence of decline ranged from 66% to 15.3% before discharge, 34% to 1.1% at 6 weeks, and 19.4% to 3.4% at 6 months.Conclusions. A large variation in reported incidence of cognitive decline after coronary artery bypass grafting can be attributed to the different criteria used to define cognitive impairment.