Influence of olfactory bulb on dendritic knob density of rat olfactory receptor neurons in vitro
Influence of olfactory bulb on dendritic knob density of rat olfactory receptor neurons in vitro
复制标题
嗅球对体外大鼠嗅觉受体神经元树突节密度的影响
DOI：
10.1016/0006-8993(85)90155-6
复制
发表时间：
1985
期刊：
影响因子：
2.9
通讯作者：
B. Menco
中科院分区：
文献类型：
--
作者：
M. Chuah;A. Farbman;B. Menco
嗅觉感受器细胞的成熟是因为它们的目标组织--嗅球的存在而促进的。胚胎大鼠嗅球(OM)器官培养中有嗅球(POB)存在时，纤毛树突结密度(1.6倍)显著高于无POB者。两组培养物无纤毛树突结密度和总结节密度无显著差异。OM和POB被分离和重组的对照组外植体也显示出纤毛树突密度增加。无论是否存在POB，嗅觉上皮的面积都是相同的。此外，扫描电子显微镜观察显示，嗅上皮的表面形态具有高度的异质性。
The maturation of olfactory receptor cells is facilitated by the presence of their target tissue, the olfactory bulb. Organ cultures of embryonic rat olfactory mucosa (OM) maintained in the presence of the presumptive olfactory bulb (POB) had a significantly higher (1.6 ×) density of ciliated dendritic knobs than those without the POB. No significant difference was found in the density of non-ciliated dendritic knobs and total knob density in these two groups of cultures. A control group of explants in which OM and POB had been separated and recombined also showed an increased ciliated dendritic knob density. The area of the olfactory epithelium was the same whether or not the POB was present. In addition, scanning electron microscopy observations revealed a high degree of heterogeneity in the surface morphology of the olfactory epithelium.