T cells and related cytokines.
T cells and related cytokines.
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T 细胞和相关细胞因子。
DOI：
10.1097/00002281-199805000-00009
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发表时间：
1998
影响因子：
5.1
通讯作者：
A. So
中科院分区：
文献类型：
--
作者：
J. Dudler;A. So
T细胞在类风湿关节炎中起着关键作用。它们可能从发病到慢性阶段持续参与发病。最近的研究表明，它们在类风湿性关节炎中的作用与巨噬细胞和间充质细胞的作用密切相关，因为它们都通过自分泌，旁分泌和细胞接触途径相互作用。本文就T细胞在类风湿关节炎发病机制中的作用作一综述。
T cells play a critical role in rheumatoid arthritis. They are probably continuously involved in pathogenesis, from the initiation to the chronic stage. As recent studies have demonstrated, the part they play in rheumatoid arthritis is closely linked to the roles of macrophages and mesenchymal cells, because they all interact through autocrine, paracrine, and cell-contact pathways. This paper reviews recent work and research regarding the specific role of T cells in the pathogenesis of rheumatoid arthritis.