Pyoderma gangrenosum Preceding the Diagnosis of Systemic Lupus erythematosus
Pyoderma gangrenosum Preceding the Diagnosis of Systemic Lupus erythematosus
复制标题
系统性红斑狼疮诊断前的坏疽脓皮病
作者：
M. Waldman;J. Callen
系统性红斑狼疮（SLE）患者常发生腿部溃疡，特别是那些有抗磷脂抗体或血管炎的患者。坏疽性脓皮病（PG）是一种特发性溃疡性嗜中性皮肤病，通常与炎症性肠病或血清阴性多关节炎有关。虽然PG样病变在抗磷脂抗体综合征患者中很常见，但PG作为SLE的前期表现的报道很少。我们提出一个病人谁开发PG约8年前发展系统性红斑狼疮。
Patients with systemic lupus erythematosus (SLE) often develop leg ulceration, particularly those with antiphospholipid antibodies or with vasculitis. Pyoderma gangrenosum (PG) is an idiopathic ulcerative neutrophilic dermatosis that is commonly associated with inflammatory bowel disease or seronegative polyarthritis. Although PG-like lesions have been commonly described in patients with the antiphospholipid antibody syndrome, the occurrence of PG as a preceding manifestation of SLE has only rarely been reported. We present a patient who developed PG roughly 8 years prior to developing SLE.
抗磷脂抗体综合征：免疫学和临床方面。
影响因子：
5
作者：
Sammaritano,LR;Gharavi,AE;Lockshin,MD
通讯作者：
Lockshin,MD