Specific genetic variation in two non-motile substrains of the model cyanobacterium Synechocystis sp. PCC 6803

Specific genetic variation in two non-motile substrains of the model cyanobacterium Synechocystis sp. PCC 6803
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模型蓝藻集胞藻属的两个非运动亚系的特定遗传变异。

DOI:
10.1007/s00343-019-7291-1
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发表时间:
2018-01
影响因子:
--
通讯作者:
Song Qin
Song Qin
中科院分区:
地学4区
文献类型:
--
作者:
Jun Chen;Wenjun Shi;Wenjun Li;Gao Chen;Song Qin

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Synechocystis sp. PCC 6803 is a model organism widely used in cyanobacterium biology and biotechnology. To know the genetic background of substrains of Synechocystis sp. PCC 6803 is important for further research and application. In this study, we reported the genome sequences of two non-motile wild-type substrains of Synechocystis sp. PCC 6803 using whole genome resequencing. 55/56 putative single nucleotide polymorphisms (SNPs) and 8/9 Indels (insertion and deletion) were identified. Among these, 47 SNPs were found in both the GT-AR and GT-CH strains, and 8 were unique to GT-AR and 9 were unique to GT-CH. All of these variations were annotated in metabolism pathway referred to KEGG database. Meanwhile, the deletion in slr0332 gene was detected in these two strains, which attributed to the non-motile phenotype of them and suggested that the insertion in spkA gene was not essential for non-motile phenotype. These resequencing data provide the genetic background information of these two strains and highlighted the microevolution over decades of laboratory cultivation.
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发表时间: 2011-10
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影响因子: --
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